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ea0029oc1.5 | Pituitary Clinical I | ICEECE2012

Initial hypothalamic involvement is the major risk factor for impaired prognosis and quality of life in childhood craniopharyngioma regardless of chosen treatment strategies: results of KRANIOPHARYNGEOM 2000

Muller H. , Gebhardt U. , Warmuth-Metz M. , Kortmann R. , Faldum A. , Pietsch T. , Gabriele C. , Sorensen N.

Hypothalamic obesity has major impact on prognosis and quality of life (QoL) in childhood craniopharyngioma (CP). The pathogenic relevance of initial hypothalamic involvement versus treatment-related hypothalamic lesions is a matter of controversy.One hundred and twenty patients were recruited prospectively during 2001 and 2007 and evaluated after 3 years of follow-up. Body mass index (BMI) and QoL at diagnosis and 36 mo after diagnosis were analyzed bas...

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Endocrine Abstracts

Initial hypothalamic involvement is the major risk factor for impaired prognosis and quality of life in childhood craniopharyngioma regardless of chosen treatment strategies: results of KRANIOPHARYNGEOM 2000

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